STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0186514Amidohydro-rel domain-containing protein. (482 aa)    
Predicted Functional Partners:
spsA
Spermidine synthase; Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate (By similarity).
   
  0.909
xdh
Xanthine dehydrogenase; Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid (By similarity).
  
 
 0.734
DDB0183921
IU_nuc_hydro domain-containing protein.
  
 
 0.542
DDB0186415
Uncharacterized protein.
  
 
 0.542
iunH
Probable ribonucleoside hydrolase; Catalyzes the hydrolysis of the N-glycosidic bond of purine and/or pyrimidine nucleosides into ribose and the base.
  
 
 0.542
hal
Probable histidine ammonia-lyase.
  
 
 0.538
DDB_G0273787
Hal-like protein DDB_G0273787/DDB_G0273081; Belongs to the PAL/histidase family.
  
 
 0.538
purD
Phosphoribosylformylglycinamidine cyclo-ligase; In the N-terminal section; belongs to the GARS family.
  
  
 0.532
udpA
Uridine phosphorylase.
    
 0.495
udpB
Uridine phosphorylase.
    
 0.495
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
Server load: low (30%) [HD]