node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDB0186269 | DDB_G0282517 | Q54NX3 | Q54SE2 | Thioredoxin; Belongs to the thioredoxin family. | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx6 subfamily. | 0.412 |
DDB0186269 | Prdx5 | Q54NX3 | Q54N76 | Thioredoxin; Belongs to the thioredoxin family. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 0.832 |
DDB0186269 | dennd10 | Q54NX3 | Q55FE3 | Thioredoxin; Belongs to the thioredoxin family. | DENN domain-containing protein 10; Guanine nucleotide exchange factor (GEF) which may be involved in the regulation of homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. | 0.428 |
DDB0186269 | gsr | Q54NX3 | Q8T137 | Thioredoxin; Belongs to the thioredoxin family. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. | 0.474 |
DDB0186269 | prdx4 | Q54NX3 | Q555L5 | Thioredoxin; Belongs to the thioredoxin family. | Peroxiredoxin-4; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.436 |
DDB0217949 | DDB_G0282517 | Q54ZW2 | Q54SE2 | Sod_Fe_C domain-containing protein. | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx6 subfamily. | 0.697 |
DDB0217949 | Prdx5 | Q54ZW2 | Q54N76 | Sod_Fe_C domain-containing protein. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 0.487 |
DDB0217949 | dennd10 | Q54ZW2 | Q55FE3 | Sod_Fe_C domain-containing protein. | DENN domain-containing protein 10; Guanine nucleotide exchange factor (GEF) which may be involved in the regulation of homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. | 0.657 |
DDB0217949 | gsr | Q54ZW2 | Q8T137 | Sod_Fe_C domain-containing protein. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. | 0.442 |
DDB0217949 | prdx4 | Q54ZW2 | Q555L5 | Sod_Fe_C domain-containing protein. | Peroxiredoxin-4; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.657 |
DDB_G0282517 | DDB0186269 | Q54SE2 | Q54NX3 | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx6 subfamily. | Thioredoxin; Belongs to the thioredoxin family. | 0.412 |
DDB_G0282517 | DDB0217949 | Q54SE2 | Q54ZW2 | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx6 subfamily. | Sod_Fe_C domain-containing protein. | 0.697 |
DDB_G0282517 | Prdx5 | Q54SE2 | Q54N76 | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx6 subfamily. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 0.650 |
DDB_G0282517 | gsr | Q54SE2 | Q8T137 | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx6 subfamily. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. | 0.666 |
DDB_G0282517 | lpd | Q54SE2 | Q54EW8 | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx6 subfamily. | Dihydrolipoyl dehydrogenase, mitochondrial; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.509 |
DDB_G0282517 | sod2 | Q54SE2 | Q55BJ9 | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx6 subfamily. | Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.696 |
Prdx5 | DDB0186269 | Q54N76 | Q54NX3 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | Thioredoxin; Belongs to the thioredoxin family. | 0.832 |
Prdx5 | DDB0217949 | Q54N76 | Q54ZW2 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | Sod_Fe_C domain-containing protein. | 0.487 |
Prdx5 | DDB_G0282517 | Q54N76 | Q54SE2 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx6 subfamily. | 0.650 |
Prdx5 | dennd10 | Q54N76 | Q55FE3 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | DENN domain-containing protein 10; Guanine nucleotide exchange factor (GEF) which may be involved in the regulation of homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. | 0.569 |