STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0186473t-SNARE coiled-coil homology domain-containing protein. (232 aa)    
Predicted Functional Partners:
DDB0188240
Uncharacterized protein.
  
 
 0.811
DDB0202238
Uncharacterized protein.
     
 0.626
Syn1A
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
    
 0.613
Syn1B
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
    
 0.613
vamp7A
Vesicle-associated membrane protein 7A; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis; Belongs to the synaptobrevin family.
    
 0.601
vamp7B
Vesicle-associated membrane protein 7B; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion (By similarity); Belongs to the synaptobrevin family.
    
 0.601
vti1A
Vesicle transport through interaction with t-SNAREs homolog 1A; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Belongs to the VTI1 family.
   
0.599
DDB0185714
Uncharacterized protein.
     
 0.595
syn5
t-SNARE family protein.
     
 0.589
DDB0205576
Syntaxin-18_N domain-containing protein.
   
 
 0.588
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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