DDB0186347 protein (Dictyostelium discoideum)

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Score

DDB0186347

MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (585 aa)

Predicted Functional Partners:

ap4e1

0.858

ap1g1

0.858

ap1b1

0.855

ap2a1-1

0.811

ap4b1

0.799

ap3d1

0.774

ap1s2

0.726

ap1s1

0.726

DDB0186653

0.714

ap2s1

0.687

Your Current Organism:

Dictyostelium discoideum

NCBI taxonomy Id: 44689
Other names: D. discoideum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDB0186347	DDB0186653	Q54NP5	Q54MT3	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	GSAP-16 domain-containing protein.	0.714
DDB0186347	ap1b1	Q54NP5	Q54X82	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	0.855
DDB0186347	ap1g1	Q54NP5	Q8I8U2	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit gamma; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	0.858
DDB0186347	ap1s1	Q54NP5	Q54WW3	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit sigma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	0.726
DDB0186347	ap1s2	Q54NP5	B0G185	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit sigma-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	0.726
DDB0186347	ap2a1-1	Q54NP5	Q86KI1	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha-2; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity).	0.811
DDB0186347	ap2s1	Q54NP5	Q54H39	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity).	0.687
DDB0186347	ap3d1	Q54NP5	Q54WN0	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway.	0.774
DDB0186347	ap4b1	Q54NP5	Q54R84	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-4 complex subunit beta; Probable component of an adaptor protein complex. Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways.	0.799
DDB0186347	ap4e1	Q54NP5	Q54VE0	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	AP-4 complex subunit epsilon; Probable component of an adaptor protein complex. Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways.	0.858
DDB0186653	DDB0186347	Q54MT3	Q54NP5	GSAP-16 domain-containing protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.714
ap1b1	DDB0186347	Q54X82	Q54NP5	AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.855
ap1b1	ap1g1	Q54X82	Q8I8U2	AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	AP-1 complex subunit gamma; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	0.967
ap1b1	ap1s1	Q54X82	Q54WW3	AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	AP-1 complex subunit sigma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	0.956
ap1b1	ap1s2	Q54X82	B0G185	AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	AP-1 complex subunit sigma-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	0.956
ap1b1	ap2a1-1	Q54X82	Q86KI1	AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	AP-2 complex subunit alpha-2; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity).	0.978
ap1b1	ap2s1	Q54X82	Q54H39	AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity).	0.984
ap1b1	ap3d1	Q54X82	Q54WN0	AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway.	0.893
ap1b1	ap4b1	Q54X82	Q54R84	AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	AP-4 complex subunit beta; Probable component of an adaptor protein complex. Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways.	0.504
ap1b1	ap4e1	Q54X82	Q54VE0	AP-1 complex subunit beta; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Also involved in early steps of phagocytosis and macropinocytosis.	AP-4 complex subunit epsilon; Probable component of an adaptor protein complex. Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways.	0.934