node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDB_G0284941 | Ndufs8 | Q54NX2 | Q86K57 | Thioredoxin domain-containing protein, mitochondrial. | Uncharacterized protein. | 0.464 |
DDB_G0284941 | cyc1 | Q54NX2 | Q54D07 | Thioredoxin domain-containing protein, mitochondrial. | Cytochrome c1, heme protein, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient ove [...] | 0.473 |
DDB_G0284941 | gsr | Q54NX2 | Q8T137 | Thioredoxin domain-containing protein, mitochondrial. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. | 0.474 |
DDB_G0284941 | mrpl11 | Q54NX2 | Q23884 | Thioredoxin domain-containing protein, mitochondrial. | 60S ribosomal protein L11, mitochondrial. | 0.583 |
DDB_G0284941 | msrA | Q54NX2 | Q551H3 | Thioredoxin domain-containing protein, mitochondrial. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). | 0.629 |
DDB_G0284941 | ndufb7 | Q54NX2 | Q54V61 | Thioredoxin domain-containing protein, mitochondrial. | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.438 |
DDB_G0284941 | ndufv1 | Q54NX2 | Q54I90 | Thioredoxin domain-containing protein, mitochondrial. | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.452 |
DDB_G0284941 | polr2b | Q54NX2 | Q54J75 | Thioredoxin domain-containing protein, mitochondrial. | DNA-directed RNA polymerase II subunit rpb2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. rpb2 is [...] | 0.537 |
DDB_G0284941 | prdx4 | Q54NX2 | Q555L5 | Thioredoxin domain-containing protein, mitochondrial. | Peroxiredoxin-4; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.422 |
DDB_G0284941 | tufm | Q54NX2 | Q54HB2 | Thioredoxin domain-containing protein, mitochondrial. | Elongation factor Tu, mitochondrial; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.432 |
Ndufs8 | DDB_G0284941 | Q86K57 | Q54NX2 | Uncharacterized protein. | Thioredoxin domain-containing protein, mitochondrial. | 0.464 |
Ndufs8 | cyc1 | Q86K57 | Q54D07 | Uncharacterized protein. | Cytochrome c1, heme protein, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient ove [...] | 0.999 |
Ndufs8 | gsr | Q86K57 | Q8T137 | Uncharacterized protein. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. | 0.655 |
Ndufs8 | ndufb7 | Q86K57 | Q54V61 | Uncharacterized protein. | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.999 |
Ndufs8 | ndufv1 | Q86K57 | Q54I90 | Uncharacterized protein. | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.999 |
Ndufs8 | polr2b | Q86K57 | Q54J75 | Uncharacterized protein. | DNA-directed RNA polymerase II subunit rpb2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. rpb2 is [...] | 0.627 |
Ndufs8 | tufm | Q86K57 | Q54HB2 | Uncharacterized protein. | Elongation factor Tu, mitochondrial; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.582 |
cyc1 | DDB_G0284941 | Q54D07 | Q54NX2 | Cytochrome c1, heme protein, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient ove [...] | Thioredoxin domain-containing protein, mitochondrial. | 0.473 |
cyc1 | Ndufs8 | Q54D07 | Q86K57 | Cytochrome c1, heme protein, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient ove [...] | Uncharacterized protein. | 0.999 |
cyc1 | ndufb7 | Q54D07 | Q54V61 | Cytochrome c1, heme protein, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient ove [...] | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.983 |