STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
samkBProbable serine/threonine-protein kinase samkB; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (593 aa)    
Predicted Functional Partners:
DDB0190646
zf-C2HC5 domain-containing protein.
      
 0.820
DDB0190641
Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family.
      
 0.820
tspD
Probable tetraspanin tspD.
   
  
 0.816
tspA
Probable tetraspanin tspA.
   
  
 0.813
tspC
Probable tetraspanin tspC.
   
  
 0.780
tspE
Probable tetraspanin tspE.
      
 0.643
mekA
Dual specificity mitogen-activated protein kinase kinase 1; Required for cAMP-mediated activation of guanylyl cyclase activity and plays an essential role in aggregation, morphogenesis, and chemotaxis. Appears to act upstream of erk1 but not erk2.
  
 
0.627
DDB_G0290859
Probable serine/threonine-protein kinase DDB_G0290859; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
  
 
 
 0.578
DDB_G0291842
Probable protein kinase DDB_G0291842; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
  
    0.521
rsmL
Rab GTPase.
    
 
 0.519
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.