STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0218645CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (207 aa)    
Predicted Functional Partners:
cdsA
Probable phosphatidate cytidylyltransferase.
   
 0.991
pikE
Phosphatidylinositol 3-kinase VPS34-like.
   
 
 0.980
pikD
Phosphatidylinositol 4-kinase; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,- trisphosphate; Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
     
 0.976
DDB0218818
PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.
   
 
 0.976
DDB_G0277537
Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family.
   
 
 0.974
pgs1
Probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
  
 
 0.963
impa1
Inositol monophosphatase; Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides. Has broad substrate specificity and can use myo-inositol monophosphates, myo- inositol 1,3-diphosphate, myo-inositol 1,4-diphosphate, scyllo- inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.
  
 
 0.958
DDB0219574
Uncharacterized protein.
   
 
 0.919
sac1
Phosphatidylinositide phosphatase SAC1; Phosphoinositide phosphatase that hydrolyzes PtdIns(3)P and PtdIns(4)P.
     
 0.918
plc
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.917
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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