STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mpiProbable mannose-6-phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (452 aa)    
Predicted Functional Partners:
gpi
Glucose-6-phosphate isomerase.
  
 
 0.993
DDB0204675
Uncharacterized protein.
  
 
 0.985
pmmA
Phosphomannomutase 1; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
  
 
 0.984
pmmB
Phosphomannomutase 2; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
  
 
 0.984
pfkA
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.954
gnpda1
Glucosamine-6-phosphate isomerase.
     
 0.943
DDB0187034
Uncharacterized protein.
  
 
 0.935
fbp
Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family.
   
 
 0.925
DDB0204621
Uncharacterized protein.
   
 
  0.901
pgmB
Probable phosphoglucomutase-2; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family.
  
 
 0.860
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.