STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rps1240S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (136 aa)    
Predicted Functional Partners:
rps10
40S ribosomal protein S10; Belongs to the eukaryotic ribosomal protein eS10 family.
   
 0.999
rpl8
60S ribosomal protein L8; Belongs to the universal ribosomal protein uL2 family.
  
 
 0.999
rpl11
60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
  
 
 0.999
rplp0
60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
  
 
 0.999
rps2
40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
  
 0.999
rpl3
60S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.999
rps17
40S ribosomal protein S17; Belongs to the eukaryotic ribosomal protein eS17 family.
   
 0.999
rps15a
40S ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family.
  
 0.999
rpl27a
60S ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family.
  
 
 0.999
rps4
40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.
   
 0.999
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.