node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDB0205063 | DDB0205957 | Q54T66 | Q54WI1 | Uncharacterized protein. | Uncharacterized protein. | 0.637 |
DDB0205063 | pho2B | Q54T66 | Q54RD6 | Uncharacterized protein. | Protein phosphatase 2A catalytic subunit B; Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway ; Belongs to the PPP phosphatase family. PP-2A subfamily. | 0.900 |
DDB0205063 | ppp4r2 | Q54T66 | Q86IL5 | Uncharacterized protein. | Serine/threonine-protein phosphatase 4 regulatory subunit 2; Probable regulatory subunit of serine/threonine-protein phosphatase 4 (PP4); Belongs to the PPP4R2 family. | 0.802 |
DDB0205063 | pppA | Q54T66 | Q54QR9 | Uncharacterized protein. | Protein phosphatase 2A scaffold subunit; Scaffolding molecule which may coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. | 0.734 |
DDB0205063 | roco11 | Q54T66 | Q6XHA5 | Uncharacterized protein. | Probable serine/threonine-protein kinase roco11; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily. | 0.841 |
DDB0205063 | roco5 | Q54T66 | Q1ZXD6 | Uncharacterized protein. | Probable serine/threonine-protein kinase roco5; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor. | 0.841 |
DDB0205063 | roco6 | Q54T66 | Q54WS5 | Uncharacterized protein. | Probable serine/threonine-protein kinase roco6; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily. | 0.841 |
DDB0205063 | roco8 | Q54T66 | Q54M77 | Uncharacterized protein. | Probable serine/threonine-protein kinase roco8; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily. | 0.841 |
DDB0205063 | smkA | Q54T66 | Q54I18 | Uncharacterized protein. | Suppressor of Mek1; Suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects. Required for proper cytokinesis during vegetative growth, timely exit from the mound stage during development, and myosin II assembly. May be a regulatory subunit of serine/threonine-protein phosphatase 4 (PP4) and may control localization of PP4 to the nucleus. Involved in the regulation of some ppp4c functions, such as developmental progression, chemotaxis, expression of stress response genes and cell movement; Belongs to the SMEK family. | 0.791 |
DDB0205957 | DDB0205063 | Q54WI1 | Q54T66 | Uncharacterized protein. | Uncharacterized protein. | 0.637 |
DDB0205957 | pho2B | Q54WI1 | Q54RD6 | Uncharacterized protein. | Protein phosphatase 2A catalytic subunit B; Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway ; Belongs to the PPP phosphatase family. PP-2A subfamily. | 0.893 |
DDB0205957 | ppp4r2 | Q54WI1 | Q86IL5 | Uncharacterized protein. | Serine/threonine-protein phosphatase 4 regulatory subunit 2; Probable regulatory subunit of serine/threonine-protein phosphatase 4 (PP4); Belongs to the PPP4R2 family. | 0.595 |
DDB0205957 | pppA | Q54WI1 | Q54QR9 | Uncharacterized protein. | Protein phosphatase 2A scaffold subunit; Scaffolding molecule which may coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. | 0.413 |
DDB0205957 | smkA | Q54WI1 | Q54I18 | Uncharacterized protein. | Suppressor of Mek1; Suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects. Required for proper cytokinesis during vegetative growth, timely exit from the mound stage during development, and myosin II assembly. May be a regulatory subunit of serine/threonine-protein phosphatase 4 (PP4) and may control localization of PP4 to the nucleus. Involved in the regulation of some ppp4c functions, such as developmental progression, chemotaxis, expression of stress response genes and cell movement; Belongs to the SMEK family. | 0.542 |
gefH | pho2B | Q8IS16 | Q54RD6 | Ras guanine nucleotide exchange factor H; Promotes the exchange of Ras-bound GDP by GTP. Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. | Protein phosphatase 2A catalytic subunit B; Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway ; Belongs to the PPP phosphatase family. PP-2A subfamily. | 0.852 |
gefH | pppA | Q8IS16 | Q54QR9 | Ras guanine nucleotide exchange factor H; Promotes the exchange of Ras-bound GDP by GTP. Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. | Protein phosphatase 2A scaffold subunit; Scaffolding molecule which may coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. | 0.852 |
pho2B | DDB0205063 | Q54RD6 | Q54T66 | Protein phosphatase 2A catalytic subunit B; Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway ; Belongs to the PPP phosphatase family. PP-2A subfamily. | Uncharacterized protein. | 0.900 |
pho2B | DDB0205957 | Q54RD6 | Q54WI1 | Protein phosphatase 2A catalytic subunit B; Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway ; Belongs to the PPP phosphatase family. PP-2A subfamily. | Uncharacterized protein. | 0.893 |
pho2B | gefH | Q54RD6 | Q8IS16 | Protein phosphatase 2A catalytic subunit B; Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway ; Belongs to the PPP phosphatase family. PP-2A subfamily. | Ras guanine nucleotide exchange factor H; Promotes the exchange of Ras-bound GDP by GTP. Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin-dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway. | 0.852 |
pho2B | ppp4r2 | Q54RD6 | Q86IL5 | Protein phosphatase 2A catalytic subunit B; Component of the Sca1 complex, a regulator of cell motility, chemotaxis and signal relay. The Sca1 complex is recruited to the plasma membrane in a chemoattractant- and F-actin- dependent manner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics and signal relay by controlling the activation of rasC and the downstream target of rapamycin complex 2 (TORC2)-Akt/protein kinase B (PKB) pathway ; Belongs to the PPP phosphatase family. PP-2A subfamily. | Serine/threonine-protein phosphatase 4 regulatory subunit 2; Probable regulatory subunit of serine/threonine-protein phosphatase 4 (PP4); Belongs to the PPP4R2 family. | 0.901 |