node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDB0230115 | DDB0230117 | Q54RI8 | Q54VK0 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | 0.814 |
DDB0230115 | DDB0230137 | Q54RI8 | Q54X84 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.783 |
DDB0230115 | FthS | Q54RI8 | Q54G53 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Formate-dihydrofolate ligase. | 0.981 |
DDB0230115 | folC | Q54RI8 | Q54CY5 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Putative folylpolyglutamate synthase; Conversion of folates to polyglutamate derivatives. | 0.783 |
DDB0230115 | ftcd | Q54RI8 | Q54JL3 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | 0.783 |
DDB0230115 | gcvP | Q54RI8 | Q54KM7 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Glycine dehydrogenase (decarboxylating), mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity). | 0.864 |
DDB0230115 | gcvT | Q54RI8 | Q54DD3 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Aminomethyltransferase, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.804 |
DDB0230115 | mtr | Q54RI8 | Q54P92 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). | 0.769 |
DDB0230115 | purD | Q54RI8 | Q54GJ2 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Phosphoribosylformylglycinamidine cyclo-ligase; In the N-terminal section; belongs to the GARS family. | 0.990 |
DDB0230115 | rpl18 | Q54RI8 | Q54VZ4 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | 60S ribosomal protein L18. | 0.880 |
DDB0230117 | DDB0230115 | Q54VK0 | Q54RI8 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | 0.814 |
DDB0230117 | DDB0230137 | Q54VK0 | Q54X84 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.783 |
DDB0230117 | FthS | Q54VK0 | Q54G53 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Formate-dihydrofolate ligase. | 0.981 |
DDB0230117 | folC | Q54VK0 | Q54CY5 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Putative folylpolyglutamate synthase; Conversion of folates to polyglutamate derivatives. | 0.785 |
DDB0230117 | ftcd | Q54VK0 | Q54JL3 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. | 0.783 |
DDB0230117 | gcvP | Q54VK0 | Q54KM7 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Glycine dehydrogenase (decarboxylating), mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity). | 0.868 |
DDB0230117 | gcvT | Q54VK0 | Q54DD3 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Aminomethyltransferase, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.804 |
DDB0230117 | mtr | Q54VK0 | Q54P92 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). | 0.772 |
DDB0230117 | purD | Q54VK0 | Q54GJ2 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | Phosphoribosylformylglycinamidine cyclo-ligase; In the N-terminal section; belongs to the GARS family. | 0.987 |
DDB0230117 | rpl18 | Q54VK0 | Q54VZ4 | Methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase. | 60S ribosomal protein L18. | 0.541 |