node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDB0190661 | DDB0219593 | Q55CT7 | Q54FQ6 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | 0.793 |
DDB0190661 | DDB_G0282683 | Q55CT7 | Q54S39 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. | 0.533 |
DDB0190661 | comG | Q55CT7 | Q54DG1 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Aldehyde dehydrogenase family 3 comG. | 0.539 |
DDB0190661 | cyp51 | Q55CT7 | Q1ZXH9 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Probable lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | 0.770 |
DDB0205558 | DDB_G0282683 | Q54U08 | Q54S39 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. | 0.437 |
DDB0205558 | DDB_G0283893 | Q54U08 | Q54QG5 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | Probable E3 ubiquitin-protein ligase DDB_G0283893; Probable E3 ubiquitin-protein ligase; Belongs to the UBR4 family. | 0.400 |
DDB0205558 | DDB_G0294577 | Q54U08 | Q1ZXG2 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | Rab GTPase. | 0.438 |
DDB0205558 | comG | Q54U08 | Q54DG1 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | Aldehyde dehydrogenase family 3 comG. | 0.434 |
DDB0218082 | DDB_G0282683 | Q54YD3 | Q54S39 | Uncharacterized protein. | Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. | 0.424 |
DDB0219593 | DDB0190661 | Q54FQ6 | Q55CT7 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.793 |
DDB0219593 | DDB_G0282683 | Q54FQ6 | Q54S39 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. | 0.479 |
DDB0219593 | comG | Q54FQ6 | Q54DG1 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Aldehyde dehydrogenase family 3 comG. | 0.596 |
DDB0219593 | cyp51 | Q54FQ6 | Q1ZXH9 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Probable lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | 0.745 |
DDB_G0282683 | DDB0190661 | Q54S39 | Q55CT7 | Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.533 |
DDB_G0282683 | DDB0205558 | Q54S39 | Q54U08 | Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | 0.437 |
DDB_G0282683 | DDB0218082 | Q54S39 | Q54YD3 | Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. | Uncharacterized protein. | 0.424 |
DDB_G0282683 | DDB0219593 | Q54S39 | Q54FQ6 | Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | 0.479 |
DDB_G0282683 | DDB_G0283893 | Q54S39 | Q54QG5 | Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. | Probable E3 ubiquitin-protein ligase DDB_G0283893; Probable E3 ubiquitin-protein ligase; Belongs to the UBR4 family. | 0.435 |
DDB_G0282683 | DDB_G0294577 | Q54S39 | Q1ZXG2 | Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. | Rab GTPase. | 0.426 |
DDB_G0282683 | comG | Q54S39 | Q54DG1 | Cytochrome b5 domain-containing protein; Belongs to the cytochrome b5 family. | Aldehyde dehydrogenase family 3 comG. | 0.424 |