STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0231514Phosphopantothenatecysteine ligase. (389 aa)    
Predicted Functional Partners:
DDB0231513
Pantothenate kinase.
     
 0.991
ppcdc
Putative phosphopantothenoylcysteine decarboxylase; Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4'- phosphopantotheine (By similarity).
    
 0.991
DDB0231518
Putative pantetheine-phosphate adenylyltransferase.
   
 0.910
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.905
ccbl
Kynurenine--oxoglutarate transaminase; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
  
  0.838
DDB0205318
RNA_helicase domain-containing protein.
   
 
 0.835
cysK
Cysteine synthase.
    
 0.818
DDB0231517
Dephospho-CoA kinase.
  
 0.817
aatB
Aspartate aminotransferase, cytoplasmic; Plays a key role in amino acid metabolism; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
    
  0.803
cysA
Cystathionine gamma-lyase; Belongs to the trans-sulfuration enzymes family.
   
 
  0.803
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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