STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbc1d5BTBC1 domain family member 5 homolog B; May act as a GTPase-activating protein for Rab family protein(s). (1016 aa)    
Predicted Functional Partners:
vps29
Vacuolar protein sorting-associated protein 29; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. The vps29-vps26-vps35 subcomplex may be involved in cargo selection.
   
 
 0.892
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. The vps29-vps26-vps35 subcomplex may be involved in cargo selection.
   
 
 0.690
vps26
Vacuolar protein sorting-associated protein 26; Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to- Golgi retrograde transport. The vps29-vps26-vps35 subcomplex may be involved in cargo selection.
   
 
 0.658
pex3
Peroxisome biogenesis factor 3; Involved in peroxisome biosynthesis; Belongs to the peroxin-3 family.
      
 0.457
DDB0229988
ADP-ribosylation factor-related.
   
 
 0.451
rab6
Ras-related protein Rab-6; Protein transport. Probably involved in vesicular traffic (By similarity).
   
 
 0.446
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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