STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB_G0281733Putative uncharacterized protein DDB_G0281733. (831 aa)    
Predicted Functional Partners:
Nup93
Nuclear pore protein.
   
 
 0.735
Nup155
Nucleoporin_N domain-containing protein.
   
 
 0.722
Nup107
Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).
   
 
 0.710
nup54
Nuclear pore complex protein nup54; Probable component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
   
 
 0.708
sec13
Protein SEC13 homolog; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 [...]
    
 
 0.700
Rae1
WD_REPEATS_REGION domain-containing protein.
   
 
 0.698
cotE
Spore coat protein SP65; Forms a triad with cellulose and pspB that is essential for spore outer layer formation.
   
 
 0.694
Nup133
Uncharacterized protein.
   
 
 0.692
nup85
Nuclear pore complex protein nup85; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane; Belongs to the nucleoporin Nup85 family.
   
 
 0.682
DDB0169145
Uncharacterized protein; Belongs to the WD repeat SEC13 family.
   
 
 0.671
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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