STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB_G0281581Uncharacterized protein. (118 aa)    
Predicted Functional Partners:
bip1-1
Luminal-binding protein 1; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER; Belongs to the heat shock protein 70 family.
 
 
 0.874
hspH
Heat shock protein 88; May function in protein folding and assembly, and disassembly of protein complexes; Belongs to the heat shock protein 70 family.
 
 
 0.766
DDB0188683
J domain-containing protein.
 
 0.765
DDB0204986
J domain-containing protein.
 
 0.757
grpE
GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
  
 
 0.751
DDB0206576
J domain-containing protein.
 
 0.738
DDB0190510
Uncharacterized protein.
  
 0.735
DDB0215234
HSCB_C domain-containing protein.
  
 0.729
dnaja1
DnaJ homolog subfamily A member 1 homolog; Co-chaperone for Hsp70 family members. Plays a role in protein transport into mitochondria and in the regulation of apoptosis via its role as co-chaperone (By similarity).
 
 0.710
DDB0204173
Uncharacterized protein.
 
 0.708
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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