STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Coexpression
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[Homology]
Score
gadAGlutamate decarboxylase A; Generates GABA from glutamate. GABA induces the release of acbA from prespore cells and induces the exposure of tagC on the surface of prestalk cells where it can convert acbA to SDF-2. Glutamate acts as a competitive inhibitor. (462 aa)    
Predicted Functional Partners:
gabT
4-aminobutyrate aminotransferase.
  
 0.985
gluD
Glutamate dehydrogenase, mitochondrial.
   
 
 0.939
glud2
Glutamate dehydrogenase 2; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.939
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.932
DDB_G0283293
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity); Belongs to the aldehyde dehydrogenase family.
   
 0.931
comG
Aldehyde dehydrogenase family 3 comG.
   
 0.930
DDB_G0276821
Putative aldehyde dehydrogenase family 7 member A1 homolog; Belongs to the aldehyde dehydrogenase family.
   
 0.929
DDB0231475
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.929
DDB0231474
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.929
DDB0231093
Cysteine dioxygenase.
     
 0.917
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.