STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0206299Uncharacterized protein. (635 aa)    
Predicted Functional Partners:
guaA
GMP synthase [glutamine-hydrolyzing].
  
 
 0.881
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase.
    
 0.770
DDB0184291
Glutamine amidotransferase type-1 domain-containing protein.
    
 0.748
DDB0205546
Glutamine amidotransferase type-1 domain-containing protein.
    
 0.748
DDB_G0275307
Glutamine amidotransferase type-1 domain-containing protein.
    
 0.748
DDB0169374
Uncharacterized protein.
  
  
 0.634
DDB_G0292024
Probable protein tyrosine phosphatase type IVA A; Belongs to the protein-tyrosine phosphatase family.
    
 
 0.546
DDB_G0272662
Probable protein tyrosine phosphatase type IVA B; Belongs to the protein-tyrosine phosphatase family.
    
 
 0.546
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
  
  
 0.545
nit1-1
Deaminated glutathione amidase; Catalyzes the hydrolysis of the amide bond in N-(4- oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
     
 0.538
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.