STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phg1bPutative phagocytic receptor 1b; Involved in adhesion and phagocytosis of hydrophilic particles. (587 aa)    
Predicted Functional Partners:
kil1
Membrane-associated sulfotransferase kil1; Sulfotransferase involved in intracellular killing of bacteria; Belongs to the sulfotransferase 1 family.
      
 0.701
rer1
Protein RER1 homolog; May be involved in protein transport along the secretory pathway; Belongs to the RER1 family.
   
  
 0.467
sibA
Integrin beta-like protein A; Implicated in cellular adhesion to substrate or phagocytic particles.
   
  
 0.456
sadA
Substrate-adhesion molecule; Involved in substrate adhesion, myosin-independent cytokinesis, organization of actin cytoskeleton, and phagocytosis.
      
 0.451
dhkH
Hybrid signal transduction histidine kinase H; Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
      
 0.450
dhkF
Hybrid signal transduction histidine kinase F; Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
      
 0.450
sigD
Probable spore coat protein sigD; May contribute to the structure of the coat at the interface between the middle, cellulosic layer and the outer, electron-dense, proteinaceous layer.
      
 0.450
Gtr1
Uncharacterized protein.
   
  
 0.450
grlC
Metabotropic glutamate receptor-like protein C; In the C-terminal section; belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
   
  
 0.449
dhkJ
Hybrid signal transduction histidine kinase J; Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
      
 0.446
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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