STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eif6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (244 aa)    
Predicted Functional Partners:
rpl3
60S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.998
rpl31
60S ribosomal protein L31; Belongs to the eukaryotic ribosomal protein eL31 family.
  
 
 0.997
rlp24
Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of nog1 to pre-60S particles. Activates and recruits ATPase AFG2 to cytoplasmic pre-60S ribosomal particles.
   
 
 0.997
rpl7
60S ribosomal protein L7; Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity).
  
 
 0.996
rpl24
60S ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family.
   
 
 0.996
nmd3
60S ribosomal export protein NMD3; Acts as an adapter for the xpo1-mediated export of the 60S ribosomal subunit.
   
 
 0.996
rpl30
60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family.
   
 
 0.996
rpl18a
60S ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family.
  
 
 0.995
mrt4
Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
  
 0.995
rpl39
60S ribosomal protein L39.
   
 
 0.993
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.