node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDB0187874 | DDB_G0283567 | Q54J54 | Q54QW5 | Uncharacterized protein. | Ragulator complex protein LAMTOR5 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). | 0.502 |
DDB0187874 | RagC | Q54J54 | Q54PK6 | Uncharacterized protein. | Uncharacterized protein. | 0.510 |
DDB0187874 | atg1 | Q54J54 | Q86CS2 | Uncharacterized protein. | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | 0.952 |
DDB0187874 | lst8 | Q54J54 | Q54D08 | Uncharacterized protein. | Protein LST8 homolog; Plays a role in regulation of adenylate cyclase and protein kinase B (PKB) activation during aggregation. Involved in both chemotaxis and signal relay; Belongs to the WD repeat LST8 family. | 0.914 |
DDB0187874 | ragA | Q54J54 | Q54IK1 | Uncharacterized protein. | Ras-related GTP-binding protein A; Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the TOR signaling cascade; Belongs to the GTR/RAG GTP-binding protein family. | 0.533 |
DDB0187874 | raptor | Q54J54 | Q55BR7 | Uncharacterized protein. | Protein raptor homolog. | 0.946 |
DDB0187874 | tor | Q54J54 | Q86C65 | Uncharacterized protein. | Serine/threonine-protein kinase tor; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Functions as a part of 2 distinct protein complexes TORC1 and TORC2. TORC1 is a rapamycin-sensitive complex that controls cell growth in response to nutrients and growth factors. The second TOR complex, TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2 but not TORC1 negatively regulates phagocytosis. TORC2-dependent regulation of the cytoskeleton may follow differential phosphorylation of pkbA. May have some protein [...] | 0.920 |
DDB0205957 | RagC | Q54WI1 | Q54PK6 | Uncharacterized protein. | Uncharacterized protein. | 0.534 |
DDB0205957 | lst8 | Q54WI1 | Q54D08 | Uncharacterized protein. | Protein LST8 homolog; Plays a role in regulation of adenylate cyclase and protein kinase B (PKB) activation during aggregation. Involved in both chemotaxis and signal relay; Belongs to the WD repeat LST8 family. | 0.961 |
DDB0205957 | ragA | Q54WI1 | Q54IK1 | Uncharacterized protein. | Ras-related GTP-binding protein A; Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the TOR signaling cascade; Belongs to the GTR/RAG GTP-binding protein family. | 0.551 |
DDB0205957 | raptor | Q54WI1 | Q55BR7 | Uncharacterized protein. | Protein raptor homolog. | 0.963 |
DDB0205957 | tor | Q54WI1 | Q86C65 | Uncharacterized protein. | Serine/threonine-protein kinase tor; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Functions as a part of 2 distinct protein complexes TORC1 and TORC2. TORC1 is a rapamycin-sensitive complex that controls cell growth in response to nutrients and growth factors. The second TOR complex, TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2 but not TORC1 negatively regulates phagocytosis. TORC2-dependent regulation of the cytoskeleton may follow differential phosphorylation of pkbA. May have some protein [...] | 0.944 |
DDB_G0283567 | DDB0187874 | Q54QW5 | Q54J54 | Ragulator complex protein LAMTOR5 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). | Uncharacterized protein. | 0.502 |
DDB_G0283567 | RagC | Q54QW5 | Q54PK6 | Ragulator complex protein LAMTOR5 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). | Uncharacterized protein. | 0.951 |
DDB_G0283567 | atg1 | Q54QW5 | Q86CS2 | Ragulator complex protein LAMTOR5 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | 0.518 |
DDB_G0283567 | febA | Q54QW5 | Q54DU8 | Ragulator complex protein LAMTOR5 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). | Eukaryotic translation initiation factor 4E-1A-binding protein homolog; Regulates assembly of the eIF4F complex. | 0.405 |
DDB_G0283567 | lst8 | Q54QW5 | Q54D08 | Ragulator complex protein LAMTOR5 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). | Protein LST8 homolog; Plays a role in regulation of adenylate cyclase and protein kinase B (PKB) activation during aggregation. Involved in both chemotaxis and signal relay; Belongs to the WD repeat LST8 family. | 0.765 |
DDB_G0283567 | ragA | Q54QW5 | Q54IK1 | Ragulator complex protein LAMTOR5 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). | Ras-related GTP-binding protein A; Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the TOR signaling cascade; Belongs to the GTR/RAG GTP-binding protein family. | 0.941 |
DDB_G0283567 | raptor | Q54QW5 | Q55BR7 | Ragulator complex protein LAMTOR5 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). | Protein raptor homolog. | 0.985 |
DDB_G0283567 | tor | Q54QW5 | Q86C65 | Ragulator complex protein LAMTOR5 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids (By similarity). | Serine/threonine-protein kinase tor; Regulates cell growth, chemotaxis, signal relay and the actin cytoskeleton. Functions as a part of 2 distinct protein complexes TORC1 and TORC2. TORC1 is a rapamycin-sensitive complex that controls cell growth in response to nutrients and growth factors. The second TOR complex, TORC2, is presumed to be indirectly negatively modulated by rapamycin and regulates actin polarization. TORC2 but not TORC1 negatively regulates phagocytosis. TORC2-dependent regulation of the cytoskeleton may follow differential phosphorylation of pkbA. May have some protein [...] | 0.651 |