STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rasVRas-like protein rasV; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (229 aa)    
Predicted Functional Partners:
roco5
Probable serine/threonine-protein kinase roco5; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor.
  
 0.793
GxcKK
Uncharacterized protein.
   
 
 0.770
gxcB
Rac guanine nucleotide exchange factor B; Involved in the regulation of the late steps of the endocytic pathway.
   
 
 0.770
nfaA
Neurofibromin-A; Regulator of the GTPase activity of Ras, mainly RasG and RasB.
   
 0.622
DDB0167574
Ras-GAP domain-containing protein.
   
 0.622
fttB
14-3-3-like protein; Belongs to the 14-3-3 family.
   
 0.610
DDB_G0291664
Probable serine/threonine-protein kinase DDB_G0291664; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
 0.604
roco8
Probable serine/threonine-protein kinase roco8; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.
  
 
 0.604
roco6
Probable serine/threonine-protein kinase roco6; May act as a serine/threonine-protein kinase and guanine- nucleotide releasing factor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.
  
 
 0.604
roco11
Probable serine/threonine-protein kinase roco11; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.
  
 
 0.604
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.