STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amdhd1Probable imidazolonepropionase. (426 aa)    
Predicted Functional Partners:
uroc1
Probable urocanate hydratase.
 
 
 0.956
hal
Probable histidine ammonia-lyase.
 
 
 0.947
ftcd
Formimidoyltetrahydrofolate cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (By similarity); In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
   
 
 0.936
acmsd
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
      
 0.765
xdh
Xanthine dehydrogenase; Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid (By similarity).
  
 
 0.734
mcee
Methylmalonyl-CoA epimerase, mitochondrial; Belongs to the methylmalonyl-CoA epimerase family.
   
  
 0.723
DDB_G0273787
Hal-like protein DDB_G0273787/DDB_G0273081; Belongs to the PAL/histidase family.
 
 
 0.722
fba
Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
      
 0.716
DDB0187533
B12-binding domain-containing protein.
   
  
 0.706
DDB0183921
IU_nuc_hydro domain-containing protein.
  
 
 0.542
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.