node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDB_G0292570 | fntA | Q54D25 | Q54RT9 | Uncharacterized protein. | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate (By similarity). | 0.977 |
DDB_G0292570 | icmt-1 | Q54D25 | Q558K8 | Uncharacterized protein. | Protein-S-isoprenylcysteine O-methyltransferase; Methylates the C-terminal cysteine residues of small GTPases and the heterotrimeric G protein gamma subunit in response to cAMP. The methylation is required for intercellular signaling and regulation of cAMP waves propagation. It also seems to induce the activity of car1, a G protein-coupled receptor which senses extracellular cAMP during the aggregation phase of development; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. | 0.981 |
DDB_G0292570 | pggt1b | Q54D25 | Q55DA3 | Uncharacterized protein. | Geranylgeranyl transferase type-1 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X; Belongs to the protein prenyltransferase subunit beta family. | 0.473 |
fntA | DDB_G0292570 | Q54RT9 | Q54D25 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate (By similarity). | Uncharacterized protein. | 0.977 |
fntA | icmt-1 | Q54RT9 | Q558K8 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate (By similarity). | Protein-S-isoprenylcysteine O-methyltransferase; Methylates the C-terminal cysteine residues of small GTPases and the heterotrimeric G protein gamma subunit in response to cAMP. The methylation is required for intercellular signaling and regulation of cAMP waves propagation. It also seems to induce the activity of car1, a G protein-coupled receptor which senses extracellular cAMP during the aggregation phase of development; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. | 0.906 |
fntA | pggt1b | Q54RT9 | Q55DA3 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate (By similarity). | Geranylgeranyl transferase type-1 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X; Belongs to the protein prenyltransferase subunit beta family. | 0.999 |
icmt-1 | DDB_G0292570 | Q558K8 | Q54D25 | Protein-S-isoprenylcysteine O-methyltransferase; Methylates the C-terminal cysteine residues of small GTPases and the heterotrimeric G protein gamma subunit in response to cAMP. The methylation is required for intercellular signaling and regulation of cAMP waves propagation. It also seems to induce the activity of car1, a G protein-coupled receptor which senses extracellular cAMP during the aggregation phase of development; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. | Uncharacterized protein. | 0.981 |
icmt-1 | fntA | Q558K8 | Q54RT9 | Protein-S-isoprenylcysteine O-methyltransferase; Methylates the C-terminal cysteine residues of small GTPases and the heterotrimeric G protein gamma subunit in response to cAMP. The methylation is required for intercellular signaling and regulation of cAMP waves propagation. It also seems to induce the activity of car1, a G protein-coupled receptor which senses extracellular cAMP during the aggregation phase of development; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate (By similarity). | 0.906 |
icmt-1 | pggt1b | Q558K8 | Q55DA3 | Protein-S-isoprenylcysteine O-methyltransferase; Methylates the C-terminal cysteine residues of small GTPases and the heterotrimeric G protein gamma subunit in response to cAMP. The methylation is required for intercellular signaling and regulation of cAMP waves propagation. It also seems to induce the activity of car1, a G protein-coupled receptor which senses extracellular cAMP during the aggregation phase of development; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. | Geranylgeranyl transferase type-1 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X; Belongs to the protein prenyltransferase subunit beta family. | 0.465 |
icmt-1 | purD | Q558K8 | Q54GJ2 | Protein-S-isoprenylcysteine O-methyltransferase; Methylates the C-terminal cysteine residues of small GTPases and the heterotrimeric G protein gamma subunit in response to cAMP. The methylation is required for intercellular signaling and regulation of cAMP waves propagation. It also seems to induce the activity of car1, a G protein-coupled receptor which senses extracellular cAMP during the aggregation phase of development; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. | Phosphoribosylformylglycinamidine cyclo-ligase; In the N-terminal section; belongs to the GARS family. | 0.569 |
pggt1b | DDB_G0292570 | Q55DA3 | Q54D25 | Geranylgeranyl transferase type-1 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X; Belongs to the protein prenyltransferase subunit beta family. | Uncharacterized protein. | 0.473 |
pggt1b | fntA | Q55DA3 | Q54RT9 | Geranylgeranyl transferase type-1 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X; Belongs to the protein prenyltransferase subunit beta family. | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate (By similarity). | 0.999 |
pggt1b | icmt-1 | Q55DA3 | Q558K8 | Geranylgeranyl transferase type-1 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X; Belongs to the protein prenyltransferase subunit beta family. | Protein-S-isoprenylcysteine O-methyltransferase; Methylates the C-terminal cysteine residues of small GTPases and the heterotrimeric G protein gamma subunit in response to cAMP. The methylation is required for intercellular signaling and regulation of cAMP waves propagation. It also seems to induce the activity of car1, a G protein-coupled receptor which senses extracellular cAMP during the aggregation phase of development; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. | 0.465 |
pggt1b | purD | Q55DA3 | Q54GJ2 | Geranylgeranyl transferase type-1 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X; Belongs to the protein prenyltransferase subunit beta family. | Phosphoribosylformylglycinamidine cyclo-ligase; In the N-terminal section; belongs to the GARS family. | 0.489 |
purD | icmt-1 | Q54GJ2 | Q558K8 | Phosphoribosylformylglycinamidine cyclo-ligase; In the N-terminal section; belongs to the GARS family. | Protein-S-isoprenylcysteine O-methyltransferase; Methylates the C-terminal cysteine residues of small GTPases and the heterotrimeric G protein gamma subunit in response to cAMP. The methylation is required for intercellular signaling and regulation of cAMP waves propagation. It also seems to induce the activity of car1, a G protein-coupled receptor which senses extracellular cAMP during the aggregation phase of development; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. | 0.569 |
purD | pggt1b | Q54GJ2 | Q55DA3 | Phosphoribosylformylglycinamidine cyclo-ligase; In the N-terminal section; belongs to the GARS family. | Geranylgeranyl transferase type-1 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X; Belongs to the protein prenyltransferase subunit beta family. | 0.489 |