STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fcsAFatty acyl-CoA synthetase A; Long chain fatty acid acyl-CoA synthetases catalyze the formation of a thiester bond between a free fatty acid and coenzyme A during fatty acid metabolic process. May mediate fatty acid retrieval from the lumen of endosomes into the cytoplasm. Belongs to the ATP-dependent AMP-binding enzyme family. (667 aa)    
Predicted Functional Partners:
DDB0190808
AMP-binding domain-containing protein.
  
  
 
0.916
fcsB
Fatty acyl-CoA synthetase B; Long chain fatty acid acyl-CoA synthetases catalyze the formation of a thiester bond between a free fatty acid and coenzyme A during fatty acid metabolic process; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
0.911
ppt3
Palmitoyl-protein thioesterase 3; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation.
   
 
 0.911
Ppt2
Uncharacterized protein.
   
 
 0.910
Ppt1
Uncharacterized protein.
   
 
 0.910
DDB0202316
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
 0.848
DDB0215301
Uncharacterized protein.
   
 
 0.821
DDB0169489
Hydrolase_4 domain-containing protein.
    
 0.811
DDB_G0284681
Uncharacterized protein.
  
 
 0.776
dgat2
Diacylglycerol O-acyltransferase 2; Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for storage lipid synthesis (By similarity).
   
 
 0.768
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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