STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpSTryptophan--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (400 aa)    
Predicted Functional Partners:
wars2
Tryptophan--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.957
leuS
Leucine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.949
serS
Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec) (By similarity).
  
 
 0.929
mileS
Probable isoleucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.920
ileS
Probable isoleucine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.916
cysS
Cysteine--tRNA ligase, cytoplasmic.
  
  
 0.903
glnS
Probable glutamine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.891
argS1
Probable arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.
  
  
 0.880
hisS
Histidine--tRNA ligase, cytoplasmic; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.867
mcysS
Probable cysteine--tRNA ligase, mitochondrial.
  
  
 0.865
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.