Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DDB0185872 | DDB0187874 | Q54Q21 | Q54J54 | PB1 domain-containing protein. | Uncharacterized protein. | 0.714 |
| DDB0185872 | atg10 | Q54Q21 | Q55EL2 | PB1 domain-containing protein. | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | 0.701 |
| DDB0185872 | atg12 | Q54Q21 | Q86CR6 | PB1 domain-containing protein. | Ubiquitin-like protein atg12; Ubiquitin-like protein involved in autophagy vesicles formation. Required for atg8 association to the vesicle membranes. Conjugated to atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme is essential for its function (By similarity); Belongs to the ATG12 family. | 0.701 |
| DDB0185872 | atg18 | Q54Q21 | Q54NA2 | PB1 domain-containing protein. | Autophagy-related protein 18; May be involved in cytoplasm to vacuole transport and autophagy; Belongs to the WD repeat SVP1 family. | 0.737 |
| DDB0185872 | atg3 | Q54Q21 | Q550A8 | PB1 domain-containing protein. | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), and autophagy. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE). This step is required for the membrane association of atg8. The formation of the atg8- phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt) (By similarity). | 0.716 |
| DDB0185872 | atg5 | Q54Q21 | Q54GT9 | PB1 domain-containing protein. | Autophagy protein 5; Involved in autophagic vesicle formation. Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate acts as an E3- like enzyme which is required for lipidation of atg8 and its association to the vesicle membranes (By similarity). | 0.731 |
| DDB0185872 | atg7 | Q54Q21 | Q86CR9 | PB1 domain-containing protein. | Ubiquitin-like modifier-activating enzyme atg7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. Activates atg12 for its conjugation with atg5 and atg8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the atg8 association to autophagosomes membranes (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | 0.714 |
| DDB0185872 | atg8 | Q54Q21 | Q86CR8 | PB1 domain-containing protein. | Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. Participates in membrane fusion events that take place in the secretory pathway (By similarity); Belongs to the ATG8 family. | 0.999 |
| DDB0185872 | atg9 | Q54Q21 | Q54NA3 | PB1 domain-containing protein. | Autophagy-related protein 9; Involved in autophagy vesicles formation. May recruit atg8 to the pre-autophagosomal structure (By similarity). Required for lipopolysaccharide (LPS)-enhanced bacterial clearance through the autophagic pathway; Belongs to the ATG9 family. | 0.738 |
| DDB0185872 | vps15 | Q54Q21 | Q54S77 | PB1 domain-containing protein. | Probable serine/threonine-protein kinase vps15; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.703 |
| DDB0187874 | DDB0185872 | Q54J54 | Q54Q21 | Uncharacterized protein. | PB1 domain-containing protein. | 0.714 |
| DDB0187874 | atg10 | Q54J54 | Q55EL2 | Uncharacterized protein. | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | 0.812 |
| DDB0187874 | atg12 | Q54J54 | Q86CR6 | Uncharacterized protein. | Ubiquitin-like protein atg12; Ubiquitin-like protein involved in autophagy vesicles formation. Required for atg8 association to the vesicle membranes. Conjugated to atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme is essential for its function (By similarity); Belongs to the ATG12 family. | 0.778 |
| DDB0187874 | atg18 | Q54J54 | Q54NA2 | Uncharacterized protein. | Autophagy-related protein 18; May be involved in cytoplasm to vacuole transport and autophagy; Belongs to the WD repeat SVP1 family. | 0.705 |
| DDB0187874 | atg3 | Q54J54 | Q550A8 | Uncharacterized protein. | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), and autophagy. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE). This step is required for the membrane association of atg8. The formation of the atg8- phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt) (By similarity). | 0.772 |
| DDB0187874 | atg5 | Q54J54 | Q54GT9 | Uncharacterized protein. | Autophagy protein 5; Involved in autophagic vesicle formation. Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate acts as an E3- like enzyme which is required for lipidation of atg8 and its association to the vesicle membranes (By similarity). | 0.775 |
| DDB0187874 | atg7 | Q54J54 | Q86CR9 | Uncharacterized protein. | Ubiquitin-like modifier-activating enzyme atg7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. Activates atg12 for its conjugation with atg5 and atg8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the atg8 association to autophagosomes membranes (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | 0.750 |
| DDB0187874 | atg8 | Q54J54 | Q86CR8 | Uncharacterized protein. | Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. Participates in membrane fusion events that take place in the secretory pathway (By similarity); Belongs to the ATG8 family. | 0.595 |
| DDB0187874 | atg9 | Q54J54 | Q54NA3 | Uncharacterized protein. | Autophagy-related protein 9; Involved in autophagy vesicles formation. May recruit atg8 to the pre-autophagosomal structure (By similarity). Required for lipopolysaccharide (LPS)-enhanced bacterial clearance through the autophagic pathway; Belongs to the ATG9 family. | 0.776 |
| DDB0187874 | vps15 | Q54J54 | Q54S77 | Uncharacterized protein. | Probable serine/threonine-protein kinase vps15; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.840 |
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