STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB0190025Uncharacterized protein. (341 aa)    
Predicted Functional Partners:
DDB_G0269284
NKAP family protein; Belongs to the NKAP family.
   
 
  0.871
slu7
Pre-mRNA-splicing factor slu7; Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron.
   
 
 0.842
prpf8
Pre-mRNA-processing-splicing factor 8 homolog; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.
    
 
 0.838
DDB0189551
MI domain-containing protein.
    
 0.829
ascc3l
Activating signal cointegrator 1 complex subunit 3-like; Belongs to the helicase family.
    
 
 0.827
fam50
Protein FAM50 homolog; Belongs to the FAM50 family.
    
  0.825
dhx8
ATP-dependent RNA helicase dhx8; Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome; Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily.
   
 0.815
Syf2
Uncharacterized protein.
   
 
 0.815
DDB0184501
Uncharacterized protein.
   
 
  0.810
fam32
DUF1754 family protein.
   
 
  0.810
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.