node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDB0188711 | DDB0189619 | Q54GL9 | Q55FZ7 | Uncharacterized protein. | Ubiquitin-like domain-containing protein. | 0.502 |
DDB0188711 | SUMO | Q54GL9 | Q8N0B4 | Uncharacterized protein. | Small ubiquitin-like protein. | 0.602 |
DDB0188711 | dstA | Q54GL9 | O00910 | Uncharacterized protein. | Signal transducer and activator of transcription A; Transcription factor that binds to 5'-TTGAATTGA-3' elements in the promoter region of target genes. Functions as repressor of the ecmB gene. Regulates the differentiation of prestalk cells during development. | 0.434 |
DDB0189619 | DDB0188711 | Q55FZ7 | Q54GL9 | Ubiquitin-like domain-containing protein. | Uncharacterized protein. | 0.502 |
DDB0189619 | SUMO | Q55FZ7 | Q8N0B4 | Ubiquitin-like domain-containing protein. | Small ubiquitin-like protein. | 0.800 |
DDB0189619 | dstA | Q55FZ7 | O00910 | Ubiquitin-like domain-containing protein. | Signal transducer and activator of transcription A; Transcription factor that binds to 5'-TTGAATTGA-3' elements in the promoter region of target genes. Functions as repressor of the ecmB gene. Regulates the differentiation of prestalk cells during development. | 0.505 |
DDB0189619 | gtf2h2 | Q55FZ7 | Q86KZ2 | Ubiquitin-like domain-containing protein. | General transcription factor IIH subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFII [...] | 0.500 |
DDB0189619 | ranA | Q55FZ7 | P33519 | Ubiquitin-like domain-containing protein. | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). | 0.500 |
DDB0189619 | repB | Q55FZ7 | O00835 | Ubiquitin-like domain-containing protein. | General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/repB, but not its helicase activity, is required for [...] | 0.499 |
DDB0189619 | repD | Q55FZ7 | Q55G81 | Ubiquitin-like domain-containing protein. | General transcription and DNA repair factor IIH helicase subunit XPD; ATP-dependent 5'-3' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATP-dependent helicase activity of XPD/repD is required for DNA opening. In [...] | 0.502 |
DDB0189619 | repE | Q55FZ7 | B0M0P5 | Ubiquitin-like domain-containing protein. | DNA damage-binding protein 1; Plays a role in DNA repair. May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation. Histone ubiquitination may be important for subsequent DNA repair (By similarity). | 0.499 |
DDB0189619 | uba2 | Q55FZ7 | Q54L40 | Ubiquitin-like domain-containing protein. | SUMO-activating enzyme subunit 2; The dimeric enzyme acts as an E1 ligase for sumo. It mediates ATP-dependent activation of sumo and formation of a thioester with a conserved cysteine residue on sae2 (By similarity); Belongs to the ubiquitin-activating E1 family. | 0.700 |
DDB0189619 | ubc9 | Q55FZ7 | Q9NGP4 | Ubiquitin-like domain-containing protein. | Sumo-conjugating enzyme ubc9; Accepts the ubiquitin-like protein sumo from the E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase. | 0.700 |
SUMO | DDB0188711 | Q8N0B4 | Q54GL9 | Small ubiquitin-like protein. | Uncharacterized protein. | 0.602 |
SUMO | DDB0189619 | Q8N0B4 | Q55FZ7 | Small ubiquitin-like protein. | Ubiquitin-like domain-containing protein. | 0.800 |
SUMO | dstA | Q8N0B4 | O00910 | Small ubiquitin-like protein. | Signal transducer and activator of transcription A; Transcription factor that binds to 5'-TTGAATTGA-3' elements in the promoter region of target genes. Functions as repressor of the ecmB gene. Regulates the differentiation of prestalk cells during development. | 0.563 |
SUMO | gtf2h2 | Q8N0B4 | Q86KZ2 | Small ubiquitin-like protein. | General transcription factor IIH subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFII [...] | 0.507 |
SUMO | ranA | Q8N0B4 | P33519 | Small ubiquitin-like protein. | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). | 0.604 |
SUMO | repB | Q8N0B4 | O00835 | Small ubiquitin-like protein. | General transcription and DNA repair factor IIH helicase subunit XPB; ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/repB, but not its helicase activity, is required for [...] | 0.499 |
SUMO | repD | Q8N0B4 | Q55G81 | Small ubiquitin-like protein. | General transcription and DNA repair factor IIH helicase subunit XPD; ATP-dependent 5'-3' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATP-dependent helicase activity of XPD/repD is required for DNA opening. In [...] | 0.516 |