Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| atg1 | atg10 | Q86CS2 | Q55EL2 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | 0.510 |
| atg1 | atg12 | Q86CS2 | Q86CR6 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | Ubiquitin-like protein atg12; Ubiquitin-like protein involved in autophagy vesicles formation. Required for atg8 association to the vesicle membranes. Conjugated to atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme is essential for its function (By similarity); Belongs to the ATG12 family. | 0.976 |
| atg1 | atg18 | Q86CS2 | Q54NA2 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | Autophagy-related protein 18; May be involved in cytoplasm to vacuole transport and autophagy; Belongs to the WD repeat SVP1 family. | 0.974 |
| atg1 | atg3 | Q86CS2 | Q550A8 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), and autophagy. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE). This step is required for the membrane association of atg8. The formation of the atg8- phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt) (By similarity). | 0.971 |
| atg1 | atg5 | Q86CS2 | Q54GT9 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | Autophagy protein 5; Involved in autophagic vesicle formation. Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate acts as an E3- like enzyme which is required for lipidation of atg8 and its association to the vesicle membranes (By similarity). | 0.979 |
| atg1 | atg7 | Q86CS2 | Q86CR9 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | Ubiquitin-like modifier-activating enzyme atg7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. Activates atg12 for its conjugation with atg5 and atg8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the atg8 association to autophagosomes membranes (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | 0.915 |
| atg1 | atg8 | Q86CS2 | Q86CR8 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. Participates in membrane fusion events that take place in the secretory pathway (By similarity); Belongs to the ATG8 family. | 0.984 |
| atg1 | atg9 | Q86CS2 | Q54NA3 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | Autophagy-related protein 9; Involved in autophagy vesicles formation. May recruit atg8 to the pre-autophagosomal structure (By similarity). Required for lipopolysaccharide (LPS)-enhanced bacterial clearance through the autophagic pathway; Belongs to the ATG9 family. | 0.981 |
| atg1 | tipD | Q86CS2 | O15736 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | Protein tipD; Not known; disruption of the gene for tipD results in morphological defects. | 0.898 |
| atg1 | vps15 | Q86CS2 | Q54S77 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | Probable serine/threonine-protein kinase vps15; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.955 |
| atg10 | atg1 | Q55EL2 | Q86CS2 | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in autophagy. Involved in the control of autophagic vacuolar cell death. Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | 0.510 |
| atg10 | atg12 | Q55EL2 | Q86CR6 | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | Ubiquitin-like protein atg12; Ubiquitin-like protein involved in autophagy vesicles formation. Required for atg8 association to the vesicle membranes. Conjugated to atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme is essential for its function (By similarity); Belongs to the ATG12 family. | 0.996 |
| atg10 | atg18 | Q55EL2 | Q54NA2 | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | Autophagy-related protein 18; May be involved in cytoplasm to vacuole transport and autophagy; Belongs to the WD repeat SVP1 family. | 0.759 |
| atg10 | atg3 | Q55EL2 | Q550A8 | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), and autophagy. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE). This step is required for the membrane association of atg8. The formation of the atg8- phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt) (By similarity). | 0.793 |
| atg10 | atg5 | Q55EL2 | Q54GT9 | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | Autophagy protein 5; Involved in autophagic vesicle formation. Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate acts as an E3- like enzyme which is required for lipidation of atg8 and its association to the vesicle membranes (By similarity). | 0.936 |
| atg10 | atg7 | Q55EL2 | Q86CR9 | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | Ubiquitin-like modifier-activating enzyme atg7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. Activates atg12 for its conjugation with atg5 and atg8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the atg8 association to autophagosomes membranes (By similarity). Required for normal survival when exposed to pathogenic bacteria S.typhimurium by promoting autophagic degradation of intracellular S.typhimurium. | 0.966 |
| atg10 | atg8 | Q55EL2 | Q86CR8 | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. Participates in membrane fusion events that take place in the secretory pathway (By similarity); Belongs to the ATG8 family. | 0.845 |
| atg10 | atg9 | Q55EL2 | Q54NA3 | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | Autophagy-related protein 9; Involved in autophagy vesicles formation. May recruit atg8 to the pre-autophagosomal structure (By similarity). Required for lipopolysaccharide (LPS)-enhanced bacterial clearance through the autophagic pathway; Belongs to the ATG9 family. | 0.836 |
| atg10 | tipD | Q55EL2 | O15736 | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | Protein tipD; Not known; disruption of the gene for tipD results in morphological defects. | 0.696 |
| atg10 | vps15 | Q55EL2 | Q54S77 | Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of atg12 to atg5. atg12 conjugation to atg5 is required for autophagy. Likely serves as an atg5-recognition molecule (By similarity); Belongs to the ATG10 family. | Probable serine/threonine-protein kinase vps15; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.904 |
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