STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZizAUncharacterized protein; Belongs to the DOCK family. (2284 aa)    
Predicted Functional Partners:
ap3d1
AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway.
   
  
 0.783
DDB0169348
Ras-GAP domain-containing protein.
      
 0.726
ZizB
Uncharacterized protein; Belongs to the DOCK family.
  
  
0.661
DocB
Uncharacterized protein; Belongs to the DOCK family.
  
 
0.648
rac1A
Rho-related protein rac1A; Overexpression promotes the formation of filopodia and membrane ruffles; Belongs to the small GTPase superfamily. Rho family.
   
 0.627
docA
Uncharacterized protein; Belongs to the DOCK family.
  
 
0.605
ZizD
Uncharacterized protein; Belongs to the DOCK family.
     
0.600
RacP
Rho GTPase.
   
 0.550
racF1
Rho-related protein racF1; Might act in concert and/or share functions with other members of the RHO family in the regulation of a subset of cytoskeletal rearrangements that are required for these processes.
   
 0.549
rac1B
Rho-related protein rac1B; Overexpression promotes the formation of filopodia and membrane ruffles.
   
 0.549
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.