STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
ubqlnUbiquilin; Stable protein which acts as an antagonist of nosA by repressing cellular differentiation after the tight-aggregate stage, when cells differentiate into two precursor cell types, prespore and prestalk cells, prior to the formation of fruiting bodies. (523 aa)    
Predicted Functional Partners:
psmD4
26S proteasome non-ATPase regulatory subunit 4; Binds and presumably selects ubiquitin-conjugates for destruction; Belongs to the proteasome subunit S5A family.
   
 
 0.987
rcbA
UV excision repair protein RAD23 homolog; May play a role both in proteasomal degradation of misfolded proteins and DNA repair; Belongs to the RAD23 family.
   
 
 0.930
UbqN
Ubiquitin-like domain-containing protein.
    
 
 0.925
DDB0185872
PB1 domain-containing protein.
   
 
 0.925
DDB0190801
Uncharacterized protein.
   
 
 0.925
adrm1-1
Proteasomal ubiquitin receptor ADRM1 homolog; Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme uchl5 at the 26S proteasome and promotes its activity (By similarity). Plays a role in the transition from growth to differentiation.
   
 
 0.918
psmD13
26S proteasome non-ATPase regulatory subunit 13; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
 
 0.908
psmD2
26S proteasome non-ATPase regulatory subunit 2; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
 
 0.893
nosA
NOSA.
   
 
 0.874
DDB_G0282185
RING zinc finger-containing protein.
   
 
 0.874
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.