STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ddo-1D-aspartate oxidase. (346 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase (decarboxylating), mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity).
   
 
 0.968
agxt
Serine--pyruvate aminotransferase; Dual metabolic roles of gluconeogenesis and glyoxylate detoxification; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.957
shmt2
Serine hydroxymethyltransferase 2; Interconversion of serine and glycine.
  
 
 0.956
shmt1
Serine hydroxymethyltransferase 1; Interconversion of serine and glycine.
  
 
 0.956
masB
Malate synthase.
  
 
 0.951
DDB0230179
Isocitrate lyase.
  
 
 0.951
srr
Probable serine racemase; May catalyze the synthesis of D-serine from L-serine. May have serine dehydratase activity (By similarity).
   
 
 0.923
tkrA
Probable 2-ketogluconate reductase; Catalyzes the NADPH-dependent reduction of 2,5-diketo-D- gluconate (25DKG) to 5-keto-D-gluconate (5KDG), 2-keto-D-gluconate (2KDG) to D-gluconate, and 2-keto-L-gulonate (2KLG) to L-idonate (IA).
   
 
 0.882
haox
Hydroxyacid oxidase; Has 2-hydroxyacid oxidase activity; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
   
 
 0.855
masA
Malate synthase.
  
 
 0.828
Your Current Organism:
Dictyostelium discoideum
NCBI taxonomy Id: 44689
Other names: D. discoideum
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