| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lboz_0176 | lepB_1 | Lboz_0176 | Lboz_1186 | Outer membrane protease. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.478 |
| Lboz_0176 | lolB | Lboz_0176 | Lboz_0347 | Outer membrane protease. | Molecular chaperone LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.471 |
| Lboz_0176 | minE | Lboz_0176 | Lboz_1679 | Outer membrane protease. | Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.722 |
| Lboz_0176 | parC | Lboz_0176 | Lboz_1970 | Outer membrane protease. | DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.780 |
| flaA | flgL | Lboz_1610 | Lboz_1143 | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | Flagellar hook-associated protein FlgL. | 0.950 |
| flaA | parC | Lboz_1610 | Lboz_1970 | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.675 |
| flgL | flaA | Lboz_1143 | Lboz_1610 | Flagellar hook-associated protein FlgL. | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.950 |
| flgL | parC | Lboz_1143 | Lboz_1970 | Flagellar hook-associated protein FlgL. | DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.664 |
| gyrB | metG | Lboz_1941 | Lboz_0622 | DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.507 |
| gyrB | parC | Lboz_1941 | Lboz_1970 | DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] | DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.995 |
| gyrB | yacG | Lboz_1941 | Lboz_0524 | DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] | DNA gyrase inhibitor YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.821 |
| lepB_1 | Lboz_0176 | Lboz_1186 | Lboz_0176 | Signal peptidase I; Belongs to the peptidase S26 family. | Outer membrane protease. | 0.478 |
| lepB_1 | lolB | Lboz_1186 | Lboz_0347 | Signal peptidase I; Belongs to the peptidase S26 family. | Molecular chaperone LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.519 |
| lepB_1 | metG | Lboz_1186 | Lboz_0622 | Signal peptidase I; Belongs to the peptidase S26 family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.464 |
| lepB_1 | minE | Lboz_1186 | Lboz_1679 | Signal peptidase I; Belongs to the peptidase S26 family. | Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.698 |
| lepB_1 | parC | Lboz_1186 | Lboz_1970 | Signal peptidase I; Belongs to the peptidase S26 family. | DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.719 |
| lolB | Lboz_0176 | Lboz_0347 | Lboz_0176 | Molecular chaperone LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Outer membrane protease. | 0.471 |
| lolB | lepB_1 | Lboz_0347 | Lboz_1186 | Molecular chaperone LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.519 |
| lolB | minE | Lboz_0347 | Lboz_1679 | Molecular chaperone LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.736 |
| lolB | parC | Lboz_0347 | Lboz_1970 | Molecular chaperone LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.694 |