STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lboz_2005Phosphoribosylglycinamide synthetase ATP-grasp (A) domain protein. (403 aa)    
Predicted Functional Partners:
accB
acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.970
Lboz_2386
Methoxymalonyl CoA synthase.
 
 
 0.922
Lboz_0102
Polyketide synthase.
 
 
 0.886
Lboz_3221
Polyketide synthase.
 
 
 0.883
Lboz_0395
Polyketide synthase.
 
 
 0.870
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.867
pksJ_2
Polyketide synthase, type I.
  
 
 0.863
birA
biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
 0.861
cysK
Cystathionine beta-synthase.
 
 0.843
Lboz_0433
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
  0.817
Your Current Organism:
Fluoribacter bozemanae
NCBI taxonomy Id: 447
Other names: ATCC 33217, CIP 103872, DSM 16523, F. bozemanae, Fluoribacter bozemaniae, Legionella bozemaniae, Legionella bozemanii, NCTC 11368, strain ALLO1, strain WIGA
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.