STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCBG_01965Uncharacterized protein. (1010 aa)    
Predicted Functional Partners:
HCBG_07693
WD domain-containing protein.
    
 0.624
HCBG_03777
Uncharacterized protein.
    
 0.617
HCBG_07517
Telomere-binding alpha subunit central domain-containing protein.
    
  0.606
HCBG_00641
Transcription initiation factor TFIID subunit 5.
    
 0.584
HCBG_01637
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 0.583
HCBG_07719
Transcription initiation factor TFIID subunit 12.
    
 0.553
HCBG_02231
BZIP domain-containing protein.
    
 0.552
HCBG_07404
Ubiquitin.
    
 0.552
HCBG_06400
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
  0.550
HCBG_04515
SCA7 domain-containing protein.
    
  0.546
Your Current Organism:
Histoplasma capsulatum G186AR
NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.