STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCBG_02675C-3 sterol dehydrogenase/C-4 decarboxylase. (355 aa)    
Predicted Functional Partners:
HCBG_08346
C-4 methylsterol oxidase; Belongs to the sterol desaturase family.
   
 0.990
HCBG_03399
3-ketosteroid reductase.
   
 0.989
HCBG_02044
Squalene epoxidase.
   
 
 0.960
HCBG_07329
Squalene synthetase.
  
 
 0.959
HCBG_09147
C-5 sterol desaturase; Belongs to the sterol desaturase family.
   
 0.954
HCBG_04301
Ergosterol biosynthetic protein.
   
 
 0.941
HCBG_00405
Cytochrome P450 sterol 14 alpha-demethylase; Belongs to the cytochrome P450 family.
 
 
 0.940
HCBG_09081
Lanosterol 14-alpha-demethylase; Belongs to the cytochrome P450 family.
 
 
 0.937
HCBG_08417
Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.
    
 
 0.936
HCBG_05244
C-8 sterol isomerase.
   
 
 0.935
Your Current Organism:
Histoplasma capsulatum G186AR
NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR
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