STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCBG_06667MGS207 protein. (480 aa)    
Predicted Functional Partners:
HCBG_08125
Orotate reductase.
  
 
 0.644
HCBG_08881
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.623
HCBG_05904
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
    
 0.616
HCBG_01214
Adenine phosphoribosyltransferase.
     
 0.594
HCBG_03461
Xanthine dehydrogenase.
  
 
 0.586
HCBG_09167
Xanthine dehydrogenase.
  
 
 0.586
HCBG_02975
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
   
  0.547
HCBG_07977
2'3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family.
     
 0.546
HCBG_00978
NADPH:adrenodoxin oxidoreductase, mitochondrial.
  
 
  0.542
HCBG_01639
RING-type domain-containing protein.
    
 0.541
Your Current Organism:
Histoplasma capsulatum G186AR
NCBI taxonomy Id: 447093
Other names: Ajellomyces capsulatus G186AR, H. capsulatum G186AR
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