Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMD88799.1Indolepyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)    
Predicted Functional Partners:
AMD88798.1
Indolepyruvate ferredoxin oxidoreductase subunit alpha; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
 
 0.992
AMD91440.1
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
 
 0.977
AMD91318.1
2-oxoglutarate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.874
AMD91317.1
2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.809
AMD89389.1
Amino acid-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.786
AMD89430.1
4Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.699
AMD88797.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.586
AMD89984.1
Iron-sulfur cluster assembly scaffold protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
  
 0.505
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
   0.497
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
    
   0.497
Your Current Organism:
Desulfovibrio fairfieldensis
NCBI taxonomy Id: 44742
Other names: ATCC 70045, D. fairfieldensis, strain FH26001/95
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