Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMD89177.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)    
Predicted Functional Partners:
AMD91417.1
DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.914
AMD90864.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.912
AMD91612.1
DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.911
AMD91416.1
PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.901
AMD89097.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
AMD89702.1
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.759
aroA
Fructose-bisphosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
    
   0.470
AMD89178.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.423
Your Current Organism:
Desulfovibrio fairfieldensis
NCBI taxonomy Id: 44742
Other names: ATCC 70045, D. fairfieldensis, strain FH26001/95
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