STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMD89229.1Glycoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.744
AMD90108.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 
 0.588
AMD90109.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 
 0.588
ppk
RNA degradosome polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
       0.484
AMD88960.1
Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.463
AMD88750.1
Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.452
AMD90155.1
Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.452
AMD89231.1
Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.440
AMD89232.1
Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.440
AMD90938.1
Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.435
Your Current Organism:
Desulfovibrio fairfieldensis
NCBI taxonomy Id: 44742
Other names: ATCC 70045, D. fairfieldensis, strain FH26001/95
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.