Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
AMD89730.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)    
Predicted Functional Partners:
AMD89729.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.962
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   0.874
AMD91007.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.766
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
   0.762
AMD89610.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.724
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.694
AMD89050.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.692
AMD90900.1
3-phosphoshikimate 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.681
AMD89097.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.673
AMD90661.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.665
Your Current Organism:
Desulfovibrio fairfieldensis
NCBI taxonomy Id: 44742
Other names: ATCC 70045, D. fairfieldensis, strain FH26001/95
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