Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMD90311.1Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (352 aa)    
Predicted Functional Partners:
AMD91654.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family.
  
     0.701
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.512
AMD90194.1
Competence protein ComF; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.443
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
 
 
 
 0.442
AMD90310.1
Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.437
AMD90790.1
Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.405
Your Current Organism:
Desulfovibrio fairfieldensis
NCBI taxonomy Id: 44742
Other names: ATCC 70045, D. fairfieldensis, strain FH26001/95
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.