Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AMD90353.1Type I secretion protein TolC; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)    
Predicted Functional Partners:
AMD91569.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.909
AMD89373.1
Hemolysin secretion protein D; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.887
AMD91568.1
Hemolysin secretion protein D; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.887
AMD89372.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.851
AMD89161.1
Efflux transporter periplasmic adaptor subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.780
AMD91507.1
Efflux transporter periplasmic adaptor subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.780
AMD90500.1
Efflux transporter periplasmic adaptor subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.780
macB
Macrolide transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.714
AMD89128.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.679
AMD89588.1
Spidroin-2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.591
Your Current Organism:
Desulfovibrio fairfieldensis
NCBI taxonomy Id: 44742
Other names: ATCC 70045, D. fairfieldensis, strain FH26001/95
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