Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMD90381.1Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)    
Predicted Functional Partners:
AMD90382.1
PTS sugar transporter; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
AMD89705.1
PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.974
AMD91574.1
PTS mannose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.963
AMD91158.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 
 0.910
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
     
 0.826
AMD89706.1
PTS sugar transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.717
AMD89776.1
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.710
AMD90384.1
Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.684
AMD88859.1
Carbohydrate phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.551
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
    0.526
Your Current Organism:
Desulfovibrio fairfieldensis
NCBI taxonomy Id: 44742
Other names: ATCC 70045, D. fairfieldensis, strain FH26001/95
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