node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SKB38542.1 | SKB38553.1 | SAMN05660903_00529 | SAMN05660903_00530 | PAS fold-containing protein. | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.634 |
SKB38542.1 | SKB38562.1 | SAMN05660903_00529 | SAMN05660903_00531 | PAS fold-containing protein. | Hypothetical protein. | 0.633 |
SKB38542.1 | SKB38577.1 | SAMN05660903_00529 | SAMN05660903_00532 | PAS fold-containing protein. | Ribosomal protein S6--L-glutamate ligase; Belongs to the RimK family. | 0.620 |
SKB38542.1 | SKB38658.1 | SAMN05660903_00529 | SAMN05660903_00533 | PAS fold-containing protein. | Uncharacterized conserved protein. | 0.633 |
SKB38542.1 | glyA | SAMN05660903_00529 | SAMN05660903_00832 | PAS fold-containing protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.518 |
SKB38553.1 | SKB38542.1 | SAMN05660903_00530 | SAMN05660903_00529 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | PAS fold-containing protein. | 0.634 |
SKB38553.1 | SKB38562.1 | SAMN05660903_00530 | SAMN05660903_00531 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Hypothetical protein. | 0.830 |
SKB38553.1 | SKB38577.1 | SAMN05660903_00530 | SAMN05660903_00532 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Ribosomal protein S6--L-glutamate ligase; Belongs to the RimK family. | 0.796 |
SKB38553.1 | SKB38658.1 | SAMN05660903_00530 | SAMN05660903_00533 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Uncharacterized conserved protein. | 0.807 |
SKB38553.1 | SKB78805.1 | SAMN05660903_00530 | SAMN05660903_02554 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Formate--tetrahydrofolate ligase. | 0.602 |
SKB38553.1 | SKB91916.1 | SAMN05660903_00530 | SAMN05660903_03255 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | methionyl-tRNA formyltransferase. | 0.762 |
SKB38553.1 | fmt | SAMN05660903_00530 | SAMN05660903_01284 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.810 |
SKB38553.1 | folD | SAMN05660903_00530 | SAMN05660903_01911 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.937 |
SKB38553.1 | glyA | SAMN05660903_00530 | SAMN05660903_00832 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.659 |
SKB38553.1 | purN | SAMN05660903_00530 | SAMN05660903_00422 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Phosphoribosylglycinamide formyltransferase-1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.873 |
SKB38562.1 | SKB38542.1 | SAMN05660903_00531 | SAMN05660903_00529 | Hypothetical protein. | PAS fold-containing protein. | 0.633 |
SKB38562.1 | SKB38553.1 | SAMN05660903_00531 | SAMN05660903_00530 | Hypothetical protein. | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.830 |
SKB38562.1 | SKB38577.1 | SAMN05660903_00531 | SAMN05660903_00532 | Hypothetical protein. | Ribosomal protein S6--L-glutamate ligase; Belongs to the RimK family. | 0.948 |
SKB38562.1 | SKB38658.1 | SAMN05660903_00531 | SAMN05660903_00533 | Hypothetical protein. | Uncharacterized conserved protein. | 0.952 |
SKB38577.1 | SKB38542.1 | SAMN05660903_00532 | SAMN05660903_00529 | Ribosomal protein S6--L-glutamate ligase; Belongs to the RimK family. | PAS fold-containing protein. | 0.620 |