node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SKB36988.1 | SKB39110.1 | SAMN05660903_00427 | SAMN05660903_00567 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.478 |
SKB36988.1 | SKB43457.1 | SAMN05660903_00427 | SAMN05660903_00753 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.926 |
SKB36988.1 | SKB47783.1 | SAMN05660903_00427 | SAMN05660903_00959 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Allosteric NADP-dependent malic enzyme. | 0.957 |
SKB36988.1 | SKB75577.1 | SAMN05660903_00427 | SAMN05660903_02387 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Glutamate synthase (ferredoxin). | 0.636 |
SKB36988.1 | mdh | SAMN05660903_00427 | SAMN05660903_02194 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.930 |
SKB36988.1 | sucD | SAMN05660903_00427 | SAMN05660903_02111 | Pyruvate kinase; Belongs to the pyruvate kinase family. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.409 |
SKB39110.1 | SKB36988.1 | SAMN05660903_00567 | SAMN05660903_00427 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.478 |
SKB39110.1 | SKB43457.1 | SAMN05660903_00567 | SAMN05660903_00753 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.468 |
SKB39110.1 | SKB47783.1 | SAMN05660903_00567 | SAMN05660903_00959 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Allosteric NADP-dependent malic enzyme. | 0.867 |
SKB39110.1 | SKB68588.1 | SAMN05660903_00567 | SAMN05660903_02058 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | propionyl-CoA carboxylase beta chain. | 0.420 |
SKB39110.1 | fumC | SAMN05660903_00567 | SAMN05660903_02075 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.976 |
SKB39110.1 | gltA | SAMN05660903_00567 | SAMN05660903_01901 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Citrate synthase; Belongs to the citrate synthase family. | 0.941 |
SKB39110.1 | mdh | SAMN05660903_00567 | SAMN05660903_02194 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.884 |
SKB39110.1 | sucC | SAMN05660903_00567 | SAMN05660903_02967 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.967 |
SKB39110.1 | sucD | SAMN05660903_00567 | SAMN05660903_02111 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.978 |
SKB43457.1 | SKB36988.1 | SAMN05660903_00753 | SAMN05660903_00427 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.926 |
SKB43457.1 | SKB39110.1 | SAMN05660903_00753 | SAMN05660903_00567 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.468 |
SKB43457.1 | SKB47783.1 | SAMN05660903_00753 | SAMN05660903_00959 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Allosteric NADP-dependent malic enzyme. | 0.933 |
SKB43457.1 | SKB68588.1 | SAMN05660903_00753 | SAMN05660903_02058 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | propionyl-CoA carboxylase beta chain. | 0.673 |
SKB43457.1 | SKB75577.1 | SAMN05660903_00753 | SAMN05660903_02387 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Glutamate synthase (ferredoxin). | 0.936 |