node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHM29651.1 | SHM67812.1 | SAMN05660826_00711 | SAMN05660826_01664 | Putative MFS transporter, AGZA family, xanthine/uracil permease. | Uracil permease. | 0.655 |
SHM29651.1 | guaA | SAMN05660826_00711 | SAMN05660826_01030 | Putative MFS transporter, AGZA family, xanthine/uracil permease. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.630 |
SHM29651.1 | guaB | SAMN05660826_00711 | SAMN05660826_01737 | Putative MFS transporter, AGZA family, xanthine/uracil permease. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.608 |
SHM29651.1 | purC | SAMN05660826_00711 | SAMN05660826_00825 | Putative MFS transporter, AGZA family, xanthine/uracil permease. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.613 |
SHM29651.1 | purD | SAMN05660826_00711 | SAMN05660826_00817 | Putative MFS transporter, AGZA family, xanthine/uracil permease. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.606 |
SHM29651.1 | purE | SAMN05660826_00711 | SAMN05660826_00826 | Putative MFS transporter, AGZA family, xanthine/uracil permease. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.681 |
SHM29651.1 | purH | SAMN05660826_00711 | SAMN05660826_00818 | Putative MFS transporter, AGZA family, xanthine/uracil permease. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.581 |
SHM29651.1 | purK | SAMN05660826_00711 | SAMN05660826_00827 | Putative MFS transporter, AGZA family, xanthine/uracil permease. | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.632 |
SHM29651.1 | purL | SAMN05660826_00711 | SAMN05660826_00822 | Putative MFS transporter, AGZA family, xanthine/uracil permease. | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.615 |
SHM29651.1 | purM | SAMN05660826_00711 | SAMN05660826_00820 | Putative MFS transporter, AGZA family, xanthine/uracil permease. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.586 |
SHM67812.1 | SHM29651.1 | SAMN05660826_01664 | SAMN05660826_00711 | Uracil permease. | Putative MFS transporter, AGZA family, xanthine/uracil permease. | 0.655 |
SHM67812.1 | guaA | SAMN05660826_01664 | SAMN05660826_01030 | Uracil permease. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.740 |
SHM67812.1 | guaB | SAMN05660826_01664 | SAMN05660826_01737 | Uracil permease. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.653 |
SHM67812.1 | purD | SAMN05660826_01664 | SAMN05660826_00817 | Uracil permease. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.425 |
SHM67812.1 | purE | SAMN05660826_01664 | SAMN05660826_00826 | Uracil permease. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.558 |
SHM67812.1 | purK | SAMN05660826_01664 | SAMN05660826_00827 | Uracil permease. | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.427 |
guaA | SHM29651.1 | SAMN05660826_01030 | SAMN05660826_00711 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Putative MFS transporter, AGZA family, xanthine/uracil permease. | 0.630 |
guaA | SHM67812.1 | SAMN05660826_01030 | SAMN05660826_01664 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Uracil permease. | 0.740 |
guaA | guaB | SAMN05660826_01030 | SAMN05660826_01737 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | purC | SAMN05660826_01030 | SAMN05660826_00825 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.844 |