STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM44757.1Porphobilinogen synthase; Belongs to the ALAD family. (314 aa)    
Predicted Functional Partners:
SHM44789.1
Uroporphyrinogen III methyltransferase / synthase.
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
 0.999
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
 
 0.998
SHM44727.1
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase.
 
 
 0.994
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.976
SHM44973.1
Cobalt-precorrin 4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
 
   
 0.821
SHM09245.1
[Acyl-carrier-protein] S-malonyltransferase.
 
    
 0.812
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
  
 0.788
SHM45153.1
Sirohydrochlorin cobaltochelatase.
     
 0.779
SHM44908.1
Cobalt-precorrin 3 C17-methyltransferase.
     
 0.775
Your Current Organism:
Caldanaerovirga acetigignens
NCBI taxonomy Id: 447595
Other names: C. acetigignens, Caldanaerovirga acetigignens Wagner et al. 2009, DSM 18802, strain JW/SA-NV4
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