STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM49143.1AAA domain-containing protein. (483 aa)    
Predicted Functional Partners:
SHM49173.1
Calcineurin-like phosphoesterase superfamily domain-containing protein.
 
 0.999
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.962
SHM49087.1
Hypothetical protein.
 
     0.955
recA
Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.939
topA
DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.843
SHM49111.1
Hypothetical protein.
     
 0.838
SHM19608.1
Hypothetical protein.
 
     0.815
SHM57280.1
D-proline reductase (dithiol) PrdA.
   
  0.803
SHM46458.1
Bifunctional non-homologous end joining protein LigD.
   
 0.780
cinA
Competence/damage-inducible protein cinA; Belongs to the CinA family.
       0.749
Your Current Organism:
Caldanaerovirga acetigignens
NCBI taxonomy Id: 447595
Other names: C. acetigignens, Caldanaerovirga acetigignens Wagner et al. 2009, DSM 18802, strain JW/SA-NV4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.